IKKγ NBD Inhibitory Peptide ( —— )

产品货号. M30314 CAS No. 372146-18-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

IKKγ NBD Inhibitory Peptide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
产品描述

A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
同义词

——
通路

Others
靶点

Other Targets
受体

——
研究领域

——
适应症

——

CAS Number

372146-18-4
分子量

3693.3
分子式

C170H259N49O42S1
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

Sequence:{Asp}{Arg}{Gln}{Ile}{Lys}{Ile}{Trp}{Phe}{Gln}{Asn}{Arg}{Arg}{Met}{Lys}{Trp}{Lys}{Lys}{Thr}{Ala}{Leu}{Asp}{Trp}{Ser}{Trp}{Leu}{Gln}{Thr}{Glu}

Zhao J, et al. Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation. PLoS Biol. 2018 Jun 11;16(6):e2004663.

计算器

产品手册

关联产品

Deacetyl asperulosid...

Ddeacetyl asperulosidic acid methyl ester is a natual product isolated from the herbs of Hedyotis diffusa Willdit can lower the blood glucose level in normal mice.
Cornoside

Cornoside and Iridoids are chemosystematic markers.
72'-Dihydroxy-3'4'-d...

72'-Dihydroxy-3'4'-dimethoxyisoflavan is a natural product.